Material Fact

CENTRO DE IMAGEM DIAGNÓSTICOS S.A. ("Company") (B3: AALR3), in compliance with paragraph 4 of article 157 of Law 6404/76 and Instruction 358/02 of the Brazilian Securities and Exchange Commission ("CVM"), hereby informs its shareholders and the market in general the first amendment to the Shareholders‘ Agreement disclosed by the Company on August 20, 2021 was signed, whereby other shareholders of the Company adhere to the agreement, having as object the totality of the shares held by such shareholders, which now totals approximately 50.46% of the common shares issued by the Company. The entire content of the Shareholders‘ Agreement was made public by Empresas.Net system.

São Paulo, August 23th, 2021.

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Gabriel Rozenberg